ENTREDX,Entrectinib 200mg

Manufactor:Bigbear Pharmaceutical Laos

Introduction:Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors.

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  • details

【Drug Name】

Name: Entrectinib Capsules

Product name: ENTREDX


200 mg


ENTREDX is a prescription medicine used to treat: 

• Adults with non-small cell lung cancer (NSCLC) that has spread to other parts of the body and is caused by an abnormal ROS1 gene. 

• Adults and children 12 years and older with solid tumors (cancer) that: 

o are caused by certain abnormal NTRK genes and 

o have spread or if surgery to remove their cancer is likely to cause severe complications, and 

o there is no satisfactory alternative treatment option or the cancer grew or spread on other treatment. 

It is not known if ENTREDX is safe and effective for use in children less than 12 years of age. 

【Recommended dosage】

• Take ENTREDX exactly as your healthcare provider tells you to take it. Do not change your dose or stop taking ENTREDX unless your healthcare provider tells you to. 

• Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with ENTREDX if you develop side effects. 

• Take ENTREDX 1 time each day with or without food. 

• Swallow whole ENTREDX capsules. Do not open, crush, chew or dissolve the capsule contents. 

• If you miss a dose of ENTREDX, take it as soon as you remember. If your next dose is due within 12 hours, skip the missed dose and take your next dose at your regular time. 

• If you vomit right after taking a dose of ENTREDX, you may take the dose again.

【side effect】

The most common side effects of ENTREDX include: 

• tiredness 

• constipation 

• change in taste 

• swelling 

• dizziness 

• diarrhea 

• nausea 

• abnormal touch sensation 

• shortness of breath 

• muscle pain 

• confusion, mental status changes, memory problems, and hallucinations 

• weight gain 

• cough 

• vomiting 

• fever 

• joint pain 

• vision changes 

These are not all the possible side effects of ENTREDX. For more information, ask your healthcare provider or 



• Store ENTREDX at  below 86°F (30°C).

Keep ENTREDX and all medicines out of the reach of children.